17-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester
This product is a lipid–PEG conjugate specifically with a protected terminal ester, PEG9 spacer, and amine functionality. It specifically enables liposome modification, conjugation, and orthogonal chemistry, offering solubility, hydrophobic anchoring, and multifunctionality.
Key Features and Benefits
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Hydrophobic Lipid Tail: Anchors strongly into liposomes, micelles, and lipid bilayers.
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Primary Amine: Couples with carboxyls, NHS esters, or activated linkers.
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t-Butyl Ester: Protects carboxyl groups for staged deprotection and orthogonal chemistry.
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PEG9 Spacer: Provides hydrophilicity, solubility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in bioconjugation and lipid-based workflows.
Applications
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Liposome Functionalization: Introduces reactive groups into lipid bilayers.
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Drug Delivery: Provides PEGylated lipid scaffolds with orthogonal chemistry.
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Probe Development: Builds multifunctional lipid–PEG probes for diagnostics and imaging.
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Organic Synthesis: Serves as a versatile intermediate for lipid–PEG linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Dissolve in chloroform, ethanol, or aqueous buffer with detergents; avoid premature hydrolysis or Boc cleavage.
This product integrates lipid anchoring with amine chemistry and a protected ester, specifically providing multifunctional scaffolds for advanced bioconjugation and delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
