1,3-Bis-aminooxy Propane
This high-purity bifunctional linker contains two terminal aminooxy groups for chemoselective oxime ligation with aldehydes or ketones under mild, aqueous conditions. The short propane spacer provides minimal steric hindrance and close proximity of reactive sites, making it especially suitable for crosslinking and polymer modification where compact linkers are desired.
Key Features and Benefits
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Dual Aminooxy Groups – Enables efficient oxime bond formation with aldehyde- or ketone-containing molecules.
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Short Propane Spacer – Offers compact molecular architecture for minimal linker length.
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Mild Reaction Conditions – Supports bioconjugation in aqueous or mixed solvent systems without harsh reagents.
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High Reactivity – Rapid and selective conjugation for efficient coupling.
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High Purity – Supplied at >95% purity for consistent and reproducible performance.
Applications
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Protein and peptide crosslinking via oxime ligation
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Small-molecule and polymer functionalization
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Hydrogel and biomaterial modification
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Site-specific labeling in chemical biology
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light
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Handling: Use anhydrous solvents (e.g., DMSO, DMF); avoid prolonged moisture exposure to preserve reactivity
This product is a compact, high-purity linker with two aminooxy groups for especially efficient oxime ligation in crosslinking and functionalization applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
