1-isothiocyanato-PEG3-Azide is a crosslinker containing an azide group and isothiocyanato group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to afford a stable triazole linkage. Isothiocyanate readily reacts with amine to form stable thiourea bond, providing an excellent tool for bioconjugation with amine containing biomolecules. The PEG spacer increases the aqueous solubility of the resulting compound.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.