Biotin-PEG6-alcohol
This product is a heterobifunctional linker containing a biotin tag, a six-unit PEG spacer, and a terminal hydroxyl group. The biotin moiety binds strongly to streptavidin, avidin, and NeutrAvidin, while the hydroxyl group serves as a versatile handle for further derivatization. The PEG6 chain improves solubility, flexibility, and accessibility, making this reagent especially ideal for bioconjugation, probe development, and affinity-based applications.
Key Features and Benefits
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Biotin Tag: Provides high-affinity binding to streptavidin and avidin systems.
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Hydroxyl Group: Acts as a modifiable site for further functionalization.
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PEG6 Spacer: Enhances solubility and reduces steric hindrance.
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Balanced Design: Offers medium-length spacing with hydrophilic character.
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High Purity: Produced to ≥95% purity for reproducibility.
Applications
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Affinity Capture: Immobilizes biomolecules on streptavidin-coated beads, chips, or surfaces.
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Bioconjugation: Provides biotin handles for labeling and detection.
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Probe Development: Builds biotinylated probes for imaging and diagnostics.
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Drug Delivery: Serves as a functional linker in targeted delivery systems.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Prepare fresh solutions; avoid repeated freeze–thaw cycles.
This product combines strong biotin binding with a modifiable hydroxyl handle on a PEG6 backbone, specifically providing a versatile tool for bioconjugation and assay design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
