Biotin-PEG12-alcohol
This product is a heterobifunctional linker with a biotin tag, a PEG12 spacer, and a terminal hydroxyl group. The biotin binds strongly to streptavidin, avidin, and NeutrAvidin while the hydroxyl group serves as a versatile handle for further chemical derivatization. The PEG12 spacer specifically improves solubility, enhances biotin accessibility, and provides long-range flexibility for bioconjugation and assay development.
Key Features and Benefits
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Biotin Tag: Provides high-affinity binding to streptavidin and avidin systems.
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Hydroxyl Group: Offers a modifiable site for further functionalization.
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PEG12 Spacer: Enhances solubility, accessibility, and spacing.
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Versatile Design: Suitable for probes, drug delivery, and bioconjugates.
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High Purity: Produced to ≥95% purity for reliable performance.
Applications
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Affinity Capture: Immobilizes biomolecules on streptavidin-coated plates, chips, or beads.
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Bioconjugation: Introduces biotin handles for labeling and detection.
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Probe Development: Builds biotinylated probes for imaging and diagnostics.
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Drug Delivery: Functions as a linker for targeted therapeutic conjugates.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Prepare fresh solutions; avoid repeated freeze–thaw cycles.
This product combines strong biotin binding with hydroxyl versatility on a long PEG12 backbone, specifically providing a robust tool for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
