β-Benzyl L-Aspartic Acid N-Carboxyanhydride is an amino acid N-carboxyanhydride (NCA) monomer derived from L-aspartic acid. Researchers specifically use it in ring-opening polymerization to synthesize benzyl-protected poly(L-aspartic acid) derivatives and related synthetic polypeptides.
Key Features and Benefits
- NCA Monomer: β-Benzyl L-Aspartic Acid N-Carboxyanhydride provides a reactive N-carboxyanhydride monomer for polypeptide synthesis.
- L-Aspartic Acid Derivative: The monomer derives from L-aspartic acid and provides an amino acid-based building block for polymer research.
- Benzyl-Protected Side Chain: A benzyl ester protects the β-carboxyl group during polymerization and subsequent synthetic steps.
- Ring-Opening Polymerization: Supports NCA ring-opening polymerization for preparing synthetic polypeptides and related polymer architectures.
- Poly(L-Aspartic Acid) Precursor: Benzyl deprotection specifically provides a route to carboxyl-rich poly(L-aspartic acid) derivatives.
- Polypeptide Synthesis: Enables preparation of homopolypeptides, copolypeptides, and other amino acid-based polymer systems.
- Functional Polymer Platform: Deprotection exposes pendant carboxyl groups specifically for subsequent conjugation and chemical modification.
Applications
- Polypeptide Synthesis: Researchers use β-Benzyl L-Aspartic Acid N-Carboxyanhydride specifically to prepare synthetic aspartate-based polypeptides.
- NCA Polymerization: Supports ring-opening polymerization with compatible initiators under suitable reaction conditions.
- Protected Polyaspartate Synthesis: Enables preparation of benzyl-protected poly(L-aspartate) and related polymer structures.
- Poly(L-Aspartic Acid) Research: Benzyl deprotection provides access to carboxyl-functional poly(L-aspartic acid) derivatives.
- Block Copolypeptide Research: Supports copolymerization with compatible NCA monomers to prepare block and multicomponent polypeptides.
- Polymer Functionalization: Deprotected carboxyl groups provide reactive sites for conjugation and further chemical modification.
- Biomaterial Research: Supports development of synthetic polypeptides and functional amino acid-based polymer materials.
Storage and Handling
- Storage: Store according to the product specification in a tightly sealed container under dry conditions. Protect from moisture and excessive heat.
- Handling: NCA monomers are moisture sensitive. Handle under dry conditions and minimize exposure to atmospheric moisture before polymerization.
This product provides a versatile NCA monomer for aspartate-based polypeptide synthesis and specifically supports ring-opening polymerization, protected polyaspartate synthesis, block copolypeptide development, and functional polymer research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

![{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester](https://e1752fbe.rocketcdn.me/wp-content/uploads/AP11945.png)




