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Methyltetrazine-PEG-silane is a novel chemical compound that combines the functional properties of both PEG and tetrazine groups. This compound contains a PEG chain attached to a silane functional group, which in turn is linked to a methyltetrazine group.

The tetrazine group is known for its ability to undergo rapid and specific bioorthogonal reactions with trans-cyclooctene (TCO) groups. This unique feature allows for the precise labeling of biomolecules, such as proteins, nucleic acids, and carbohydrates, in living cells and organisms. In addition, the PEG chain provides improved solubility and stability to the labeled biomolecules.

Methyltetrazine-PEG-silane has been utilized in various applications in pharmaceutical research and development, such as in the design and development of imaging agents for diagnosis and monitoring of diseases. The bioorthogonal reaction between the tetrazine group of Methyltetrazine-PEG-silane and TCO-labeled imaging agents enables the selective and efficient targeting of specific cells or tissues, allowing for high-resolution imaging and early detection of diseases.

Methyltetrazine-PEG-silane

Cat# Name Structure M.W. Purity Pricing
AP11833Methyltetrazine-PEG5-triethoxysilane639.82≥95% Pricing

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