m-PEG-Acrylate (m-PEG-ACR) is a linear monofunctional PEG reagent with acrylate functionality, which is easily polymerized, and acrylate also reacts with thiols via thiol-ene reaction by forming thioether bonds . PEG can increase solubility and stability, and it is commonly used to prepare PEG hydrogels, which can be used to inhibit the non-specific binding of charged molecules to the modified surface.