Propargyl-PEG-CH2CO2tBu contains a propargyl functional group (-C≡CH) attached to the PEG chain and a tert-butyl ester group (-CO2tBu) attached to the terminal end of the PEG chain.
Propargyl-PEG-CH2CO2tBu has been used extensively in the development of new drugs, particularly in the area of cancer research. The propargyl group can be used for click chemistry reactions, which allows for the conjugation of small molecules or therapeutic agents to the PEG chain. This enables the design of drug delivery systems that can target specific cancer cells, improving the effectiveness of treatment while reducing side effects.
The tert-butyl ester group provides protection for the PEG chain during the conjugation process, which can be removed under specific conditions to release the conjugated drug molecule. This approach has been used in the development of prodrug molecules, where the drug is only released after reaching the desired target site, minimizing toxicity and improving the therapeutic index.
Propargyl-PEG-CH2CO2tBu
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP12292 | Propargyl-PEG4-CH2CO2tBu | Pricing | |
| AP12293 | Propargyl-PEG5-CH2CO2tBu | Pricing |
