Folate-PEG3-Azide (CAS: 1313026-32-2)
Description:
Folate-PEG3-Azide is a targeted bioconjugation compound designed to link folic acid with a PEG spacer and an azide group. This design enables efficient delivery to cells with folate receptors, commonly found in certain cancers, making it useful for targeted drug delivery and imaging.
Key Features:
- Folic Acid Targeting: Recognizes folate receptors on cancer cells, allowing selective delivery.
- PEG3 Spacer: Enhances solubility and reduces size-related obstacles for smooth conjugation.
- Azide Group: Allows click chemistry reactions, easily attaching to alkyne-containing molecules.
Applications:
- Targeted Drug Delivery: Connects with therapeutic agents for precise delivery to folate receptor-positive cells, improving treatment accuracy.
- Bioconjugation: Easily attaches to proteins, peptides, or other molecules, aiding diagnostics and therapeutic development.
- Imaging: Enables labeling for visualizing folate receptor-positive cells, useful in research and diagnostics.
Storage:
Keep at -20°C, shielded from light and moisture, to ensure stability.
Ref:
Folate-Targeted PEG as a Potential Carrier for Carboplatin Analogs. Synthesis and in Vitro Studies Olga Aronov, Aviva T. Horowitz, Alberto Gabizon, and Dan Gibson Bioconjugate Chemistry 2003 14 (3), 563-574 DOI: 10.1021/bc025642l
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
