5(6)-Carboxyrhodamine 110 PEG3 Azide
This product is a fluorescent probe combining 5(6)-carboxyrhodamine 110 dye, a PEG3 spacer, and a terminal azide. The rhodamine 110 fluorophore delivers bright green fluorescence with high photostability. The azide specifically enables CuAAC or SPAAC click chemistry with alkyne partners. The PEG3 spacer specifically improves solubility, reduces steric hindrance, and enhances accessibility for labeling, imaging, and conjugation.
Key Features and Benefits
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Bright Fluorophore: Rhodamine 110 provides intense green fluorescence and high sensitivity.
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Azide Group: Supports CuAAC or SPAAC click chemistry with alkyne partners.
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PEG3 Spacer: Enhances solubility and probe accessibility.
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Dual Functionality: Combines fluorescence detection with bioorthogonal reactivity.
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High Purity: Manufactured to ≥95% purity for reliable performance.
Applications
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Fluorescent Labeling: Tags biomolecules, peptides, or nanoparticles for detection.
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Bioorthogonal Conjugation: Couples selectively to alkyne-modified targets.
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Cell Imaging: Provides bright, photostable green fluorescence for microscopy.
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Probe Development: Serves as a multifunctional building block for diagnostics.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Protect from prolonged light exposure; prepare fresh solutions before use.
This product integrates strong fluorescence with azide click reactivity in a PEG3 framework, specifically offering a versatile tool for labeling, imaging, and conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
