PLGA Cy5 Capped, MW 10K is a high-molecular-weight, Cy5-terminated fluorescent biodegradable PLGA copolymer featuring high tissue penetration and low-background deep-red fluorescence, tailored for long-term in vivo biological tracing and prolonged sustained drug delivery imaging. It supports customizable molecular weight and diverse PLGA composition ratios, meeting advanced long-cycle biomedical formulation and imaging research demands.
Basic Specifications
Alternative Name: Cyanine 5-PLGA, Cy5-PLGA
PLGA Composition: 50:50, 65:35, 75:25, 85:15, Custom
Molecular Weight: 10K, Custom
Appearance: Blue to dark blue or purple solid
Key Features and Benefits
Cy5 Fluorescent Capped: Terminal Cy5 deep-red fluorophore functionalization delivers excellent tissue penetration and minimal background interference. It enables high-sensitivity, long-term real-time fluorescence tracking and quantitative detection without additional staining, perfectly suited for deep-tissue and long-cycle in vivo imaging applications.
Versatile PLGA Ratio Options: Covers standard 50:50, 65:35, 75:25, 85:15 ratios and fully customized formulations. Precise ratio adjustment regulates polymer hydrophobicity, degradation cycle and particle morphology to adapt to various long-term sustained-release and imaging scenarios.
Customizable High Molecular Weight: Standard 10K molecular weight forms dense polymer chain entanglement, providing superior structural rigidity and particle stability compared to medium and low MW PLGA. Custom molecular weight service supports personalized design for diverse long-cycle formulation requirements.
Excellent Biocompatibility & Biodegradability: Possesses superior physiological biosafety, fully hydrolyzing into non-toxic lactic acid and glycolic acid. No inflammatory or toxic side effects, suitable for long-term in vivo imaging and sustained-release carrier research.
Ultra-Stable Fluorescence Performance: Professional terminal capping technology effectively prevents fluorophore shedding and fluorescence quenching. It maintains stable, high-sensitivity fluorescent signals throughout long-term particle circulation, storage and slow polymer degradation.
Applications
Long-Term Deep-Tissue Biological Tracing: Ideal for prolonged in vitro and in vivo tracking of PLGA nanoparticles and microspheres, supporting deep-tissue distribution analysis and long-cycle biological behavior monitoring.
Prolonged Sustained Drug Delivery Imaging: Enables visual monitoring of long-term drug carrier degradation, in vivo accumulation, circulation retention and sustained release kinetics for long-acting formulation development.
Long-Cycle Biomedical Fluorescent Labeling: Serves as a high-stability self-fluorescent polymer matrix for long-term degradable biomaterial labeling, biological distribution evaluation and persistent optical imaging research.
High-Stability Custom Formulation Research: Leverages adjustable molecular weight and multi-ratio PLGA composition to support personalized preparation of high-stability long-acting drug delivery carriers.
Storage and Handling
Storage: Store at –20 °C in a sealed, dry, light-proof and moisture-proof container.
Handling: Avoid strong light exposure, repeated freeze-thaw cycles and high-temperature environments to prevent fluorescence quenching and premature polymer hydrolysis.
PLGA Cy5 Capped, MW 10K integrates high-stability polymer structure, long-cycle tunable degradability and high-penetration Cy5 deep-red fluorescence, specially optimized for long-term deep-tissue tracing, prolonged sustained drug delivery imaging and high-performance customized biomaterial research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.