PLGA-di-acid, MW 20K

PLGA-di-acid, MW 20K is a high-molecular-weight linear biodegradable polymer terminated with dual carboxylic acid groups on both chain ends. Synthesized from D,L-lactide and glycolide monomers, this PLGA-diacid supports multiple adjustable lactide-glycolide ratios ranging from standard 50:50, 65:35, 75:25, 85:15 to fully customized formulations. Benefiting from its longer molecular chain structure compared with lower MW analogs, the 20K grade exhibits significantly improved structural integrity, slower degradation kinetics, and better colloidal stability in biological environments. The symmetric bifunctional carboxyl terminals maintain reliable coupling reactivity, enabling efficient fabrication of high-stability block copolymers, densely crosslinked hydrogel networks, and long-circulating drug delivery nanoparticles. Possessing excellent biocompatibility and non-toxic metabolic degradation products, this high-molecular PLGA-diacid is particularly suitable for designing long-term sustained-release systems, durable biomaterial scaffolds, and high-stability biomedical conjugates.