Propargyl-PEG1-alcohol
This product is a compact PEG1 linker featuring a terminal alkyne for click chemistry and a hydroxyl group for derivatization. The short PEG1 spacer provides minimal but effective hydrophilicity, making it especially useful for bioconjugation, surface modification, and synthetic chemistry applications.
Key Features and Benefits:
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Propargyl Group: Enables CuAAC or SPAAC click chemistry with azides.
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Hydroxyl Group: Serves as a versatile handle for further functionalization.
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PEG1 Spacer: Compact chain minimizes steric hindrance while enhancing solubility.
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High Purity: Ensures reproducibility in conjugation workflows.
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Dual Reactivity: Supports orthogonal and multistep synthesis.
Applications:
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Click Chemistry: Azide–alkyne ligation for orthogonal labeling and conjugation.
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Bioconjugation: Facilitates protein, peptide, or small-molecule modification.
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Drug Delivery: Provides PEGylated functionality for solubility and stability.
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Surface Functionalization: Functionalizes polymers, nanoparticles, and hydrogels.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve alkyne and hydroxyl integrity.
This product provides compact PEG spacing with alkyne and hydroxyl reactivity, making it an especially versatile building block for bioconjugation and material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
