3-Azidopropylamine Hydrochloride (CAS: 70017-54-8)
3-Azidopropylamine Hydrochloride is a water-soluble linker with both azide (-N₃) and amine (-NH₂) groups. The amine reacts with activated esters like NHS, while the azide participates in click chemistry through CuAAC reactions, making it ideal for bioconjugation and chemical synthesis.
Key Features:
- Molecular Formula: C₃H₉ClN₄
- Molecular Weight: 136.59 g/mol
- Solubility: Soluble in water, DMSO, DMF, dichloromethane, THF, and chloroform
3-Azidopropylamine Applications:
- Bioconjugation:
- Introduces azide groups into carboxyl-containing molecules, enabling click chemistry reactions.
- Peptide Synthesis:
- Modifies peptides through reactions with activated carboxyl groups, allowing azide incorporation.
Handling and Storage:
- Appearance: White crystalline solid
- Storage: Store at -20°C in the dark; stable for 24 months.
- Transportation: Stable at room temperature for up to 3 weeks if kept dry.
This linker is commonly used in research for biomolecule labeling, click chemistry, and synthetic modifications.
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