Azido-PEG8-NHS Ester
CAS: 1204834-00-3
Description:
Azido-PEG8-NHS Ester is a versatile linker containing an azide group, a PEG8 (polyethylene glycol) spacer, and an NHS (N-hydroxysuccinimide) ester. The azide group enables bioorthogonal “click chemistry” with alkyne-functionalized molecules. The NHS ester reacts efficiently with primary amines to form stable amide bonds. This compound is widely used for bioconjugation, protein labeling, and drug delivery applications.
Key Features:
- Azide Group: Enables copper-free or copper-catalyzed click chemistry with alkyne groups, ideal for selective conjugation.
- NHS Ester: Reacts with primary amines (NH2) to form stable covalent amide bonds, useful in bioconjugation.
- PEG8 Spacer: Enhances solubility and flexibility, reducing steric hindrance and increasing biocompatibility.
Applications:
- Bioconjugation: Used for linking biomolecules through the azide-alkyne click reaction and amine-based conjugation.
- Protein and Antibody Labeling: Facilitates the selective labeling of proteins or antibodies for imaging or therapeutic applications.
- Drug Delivery Systems: Useful in conjugating therapeutic agents to biomolecules for targeted drug delivery.
- Cellular Imaging: Enables precise and specific labeling of biomolecules for imaging studies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
