Azido-PEG12-acid
This product is a bifunctional PEG12 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. The PEG12 spacer provides excellent solubility and flexibility, making it especially useful for bioconjugation, drug delivery, and surface modification.
Key Features and Benefits:
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Azide Group: Supports CuAAC and SPAAC click chemistry with alkyne partners.
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Carboxylic Acid Group: Couples with primary amines to form stable amide bonds.
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PEG12 Spacer: Long hydrophilic chain enhances solubility and reduces steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Dual Reactivity: Suitable for orthogonal and stepwise conjugation strategies.
Applications:
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Click Chemistry: Bioorthogonal conjugation with alkyne-bearing molecules.
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Bioconjugation: Versatile linker for proteins, peptides, and polymers.
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Drug Delivery: PEGylated linker improves solubility and pharmacokinetics.
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Surface Functionalization: Modify nanoparticles, hydrogels, or biomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain reactivity.
This product combines azide click chemistry with carboxyl reactivity in a long PEG spacer, specifically offering flexibility for advanced conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
