Azido-PEG5-acid
This product is a bifunctional PEG5 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. The PEG5 spacer provides hydrophilicity, flexibility, and reduced steric hindrance, making it an especially versatile reagent for bioconjugation, drug delivery, and surface functionalization.
Key Features and Benefits:
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Azide Group: Supports CuAAC or SPAAC click chemistry with alkyne partners.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG5 Spacer: Balances solubility, flexibility, and compact spacing.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Dual Reactivity: Enables orthogonal and stepwise conjugation strategies.
Applications:
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Click Chemistry: Bioorthogonal labeling through azide–alkyne ligation.
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Bioconjugation: Dual-functional linker for proteins, peptides, and biomolecules.
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Drug Delivery: Improves solubility, pharmacokinetics, and targeting capability.
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Surface Modification: Functionalizes nanoparticles, polymers, and hydrogels.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and acid stability.
This product combines click-ready azide chemistry with a reactive carboxyl group in a compact PEG spacer, making it especially useful for multifunctional bioconjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
