4-Methyl-4-(pyridin-2-yldisulfanyl)-pentanoic acid is a chemical compound used in bioconjugation, particularly in the development of antibody-drug conjugates (ADCs). It consists of a pyridine ring linked to pentanoic acid via a disulfide bond.
Key Features:
- Pyridine Ring: Provides stability and may influence solubility and binding properties.
- Disulfide Bond (SS): Enables cleavage under reducing conditions for controlled release of the drug.
- 4-Methyl Group: Offers steric hindrance that may enhance selectivity in conjugation reactions.
Applications:
- Antibody-Drug Conjugates (ADCs): Used as a linker to attach cytotoxic drugs to antibodies for targeted cancer therapy.
- Protein and Peptide Conjugation: Facilitates the attachment of drugs to proteins or peptides for selective delivery.
- Drug Delivery Systems: Supports controlled drug release mechanisms in targeted therapies.
This compound is useful in the development of targeted therapeutics, offering flexibility in drug design and delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
