N6-Bz-5′-O-DMTr-2′-O-hexadecanyl adenosine 3′-CED phosphoramidite (CAS: 2382942-35-8)
N6-Bz-5′-O-DMTr-2′-O-hexadecanyl adenosine 3′-CED phosphoramidite is a key reagent for oligonucleotide synthesis. It combines N6-benzoyl (Bz) for selective protection, 5′-O-DMTr for efficient coupling, and 2′-O-hexadecanyl to improve stability and lipophilicity. The 3′-CED phosphoramidite ensures high-precision, reliable synthesis.
Key Features:
- N6-Benzoyl Protection: Safeguards the adenosine base for selective reactivity.
- 5′-O-DMTr Group: Enhances coupling and allows controlled deprotection.
- 2′-O-Hexadecanyl: Boosts lipophilicity and stabilizes oligonucleotides.
- 3′-CED Phosphoramidite: Ensures high-efficiency and precise synthesis.
Applications:
- Oligonucleotide Synthesis: Perfect for creating stable, modified oligonucleotides.
- Nucleic Acid Research: Ideal for developing nucleic acids with enhanced properties.
- Therapeutic Development: Useful for designing oligonucleotides in gene therapy and drug discovery.
Advantages:
- Efficient Synthesis: Delivers reliable, high-quality oligonucleotides.
- Enhanced Stability: The 2′-O-hexadecanyl modification improves durability.
- Selective Protection: The N6-Bz and 5′-O-DMTr groups ensure controlled protection and deprotection.
N6-Bz-5′-O-DMTr-2′-O-hexadecanyl adenosine 3′-CED phosphoramidite is ideal for researchers needing reliable, stable reagents for oligonucleotide synthesis and therapeutic development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
