APDye™ 800 Picolyl Azide is a next-generation, sterically shielded near-infrared dye, nearly identical to IRDye® 800CW and DyLight® 800. Its two PEG arms prevent unwanted associations, significantly boosting fluorescence brightness. Absorbing at 777 nm and emitting at 794 nm, it’s ideal for imaging systems using the 800 nm channel.
Moreover, this advanced probe includes a copper-chelating motif, which increases the Cu(I) concentration at the reaction site. This feature speeds up the CuAAC reaction, making it faster and more biocompatible for precise labeling of azide-labeled biomolecules.
Key Features:
- Sterically Shielded: PEG arms prevent associations, enhancing brightness.
- Near-IR Fluorescence: Absorbs at 777 nm, emits at 794 nm, perfect for 800 nm imaging.
- Boosted CuAAC Efficiency: Copper-chelating design accelerates click reactions.
- Water-Soluble: Easily dissolves in water, ensuring wide application use.
Applications:
- Imaging: Provides high-brightness for in vivo and in vitro imaging.
- Flow Cytometry: Excellent for near-IR labeling and cellular analysis.
- Bioconjugation: Efficiently tags azide-labeled biomolecules for click chemistry.
Storage:
Store in a cool, dry place, protected from light, to preserve stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.