Carbamic acid, C29 bis[2-(2-hydroxyethoxy)ethyl], 9H-fluoren-9-ylmethyl ester (9CI)

Carbamic acid, C29 bis[2-(2-hydroxyethoxy)ethyl], 9H-fluoren-9-ylmethyl ester (9CI)

This product is an Fmoc-protected bis(PEG)-carbamate derivative. It features hydroxyl-functionalized PEG side chains for hydrophilicity and flexibility, while the Fmoc group provides base-labile protection, making it a useful intermediate for peptide synthesis and orthogonal conjugation strategies.

Key Features and Benefits:

• Fmoc Protection: Provides base-labile carbamate protection for stepwise synthesis.

• PEGylated Chains: Hydroxyethoxy groups enhance solubility and reduce steric hindrance.

• Carbamate Chemistry: Stable and versatile linkage for biomolecule modification.

• High Purity: Ensures reproducibility in peptide synthesis and conjugation workflows.

• Orthogonal Design: Enables multifunctional synthetic strategies.

Applications:

• Peptide Synthesis: Used as an Fmoc-protected intermediate in solid-phase peptide chemistry.

• Bioconjugation: Facilitates orthogonal conjugation with PEGylated side chains.

• Drug Delivery: Provides PEGylated carbamate scaffolds for solubility and stability.

• Material Science: Useful in PEG-based polymers and functionalized scaffolds.

Storage and Handling:

• Storage: Store at –20 °C, protected from light and moisture.

• Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain stability.

This product combines PEGylated functionality with Fmoc-protection, making it an especially efficient building block for peptide synthesis, conjugation, and advanced material design.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.