Bis-PEG2-endo-BCN
This product is a homobifunctional PEG linker containing two endo-bicyclo[6.1.0]nonyne (BCN) groups connected by PEG2 spacers. It specifically enables copper-free click chemistry with azides, offering solubility, compact flexibility, and dual reactivity.
Key Features and Benefits
-
Dual BCN Groups: React rapidly with azides via SPAAC copper-free click chemistry.
-
PEG2 Spacers: Provide solubility and compact linker length.
-
Bioorthogonal Reactivity: Ensures fast, selective conjugation under physiological conditions.
-
Homobifunctional Design: Enables symmetric crosslinking and multivalent modifications.
-
High Purity: Guarantees reproducibility in sensitive bioconjugation workflows.
Applications
-
Bioconjugation: Links azide-modified biomolecules using BCN click chemistry.
-
Crosslinking: Connects two azide-containing molecules or surfaces.
-
Probe Development: Builds multifunctional probes for imaging and diagnostics.
-
Drug Delivery: Provides PEG scaffolds with dual bioorthogonal reactivity.
Storage and Handling
-
Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
-
Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates two BCN click handles with PEG2 linkers, specifically offering compact, soluble, and efficient tools for dual conjugation strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
