Propargyl-PEG14-alcohol
This product is a heterobifunctional PEG linker with a terminal propargyl (alkyne) group for click chemistry and a hydroxyl group for further derivatization. The PEG14 chain provides excellent solubility, extended spacing, and flexibility, making it especially effective for probe development, drug delivery, and advanced bioconjugation.
Key Features and Benefits:
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Propargyl Group: Supports CuAAC or SPAAC click chemistry with azides.
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Hydroxyl Group: Offers modifiable functionality for extended synthetic strategies.
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PEG14 Spacer: Enhances solubility, hydrophilicity, and steric accessibility.
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Dual Functionality: Provides both click-ready and modifiable handles.
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High Purity: Ensures reproducibility in sensitive applications.
Applications:
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Bioconjugation: Links biomolecules through click chemistry and hydroxyl derivatization.
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Probe Development: Builds multifunctional alkyne-modified probes.
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Drug Delivery: Provides long-chain PEG scaffolds with improved solubility.
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Material Science: Functionalizes polymers, nanoparticles, and advanced surfaces.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain stability.
This product integrates click-ready alkyne reactivity with a hydroxyl handle in a PEG14 scaffold, specifically offering superior solubility and spacing for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
