Bis-PEG4-PFP ester
This product is a homobifunctional PEG linker containing two pentafluorophenyl (PFP) ester groups connected by a PEG4 spacer. It specifically enables efficient crosslinking of amine-containing molecules, offering solubility, flexibility, and strong reactivity for bioconjugation and materials modification.
Key Features and Benefits
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Dual PFP Esters: React efficiently with primary amines to form stable amide bonds.
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PEG4 Spacer: Provides solubility, flexibility, and moderate chain length.
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Homobifunctional Design: Enables symmetric crosslinking of biomolecules or polymers.
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High Reactivity: PFP esters show enhanced stability and reactivity compared to NHS esters.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Crosslinks proteins, peptides, or small molecules via amine coupling.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEG scaffolds with reactive amine-coupling handles.
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Material Science: Functionalizes nanoparticles, surfaces, and polymers with PEGylation.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates dual PFP ester reactivity with a PEG4 spacer, specifically offering strong amine coupling in a soluble, flexible scaffold.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
