N-Boc-N-bis(PEG3-OH)
This product is a multifunctional PEG building block containing a Boc-protected amine core and two PEG3 arms terminated with hydroxyl groups. The Boc group protects the central amine for orthogonal deprotection, while the hydroxyl groups provide versatile handles for further derivatization. The PEG3 arms improve solubility and flexibility, making this reagent especially suitable for bioconjugation, polymer modification, and drug delivery design.
Key Features and Benefits
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Boc-Protected Amine: Allows orthogonal reactivity after selective deprotection.
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Dual Hydroxyl Groups: Provide modifiable handles for diverse conjugations.
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PEG3 Spacers: Improve solubility, flexibility, and reduce steric hindrance.
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Multifunctional Core: Supports stepwise or multivalent modifications.
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High Purity: Produced to ≥95% purity for reliable performance.
Applications
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Bioconjugation: Serves as a scaffold for attaching biomolecules.
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Polymer and Material Science: Introduces PEG functionality into polymer systems.
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Drug Delivery: Acts as a modular linker in therapeutic formulations.
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Probe Development: Builds multifunctional intermediates for imaging and diagnostics.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Remove Boc under mild acidic conditions; use hydroxyls for derivatization.
This product combines orthogonal Boc protection with dual hydroxyl functionality in a PEG3 framework, specifically offering a versatile tool for controlled conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
