Lipoamide-PEG11-Mal
This product is a heterobifunctional linker featuring a lipoamide group, an eleven-unit PEG spacer, and a terminal maleimide. The lipoamide provides strong, reversible binding to thiol-rich surfaces such as gold or proteins via disulfide exchange, while the maleimide reacts selectively with thiols to form stable thioether bonds. The PEG11 spacer improves solubility, flexibility, and spacing, making this reagent especially valuable for surface modification, nanotechnology, and bioconjugation.
Key Features and Benefits
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Lipoamide Group: Anchors to thiol-rich biomolecules or surfaces.
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Maleimide Group: Reacts selectively with thiols for stable conjugation.
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PEG11 Spacer: Enhances water solubility and provides extended spacing.
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Dual Reactivity: Supports both reversible and stable thiol interactions.
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High Purity: Produced to ≥95% purity for reproducible performance.
Applications
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Surface Modification: Functionalizes gold nanoparticles, quantum dots, or thiol-coated surfaces.
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Bioconjugation: Links thiol-containing proteins, peptides, or carriers.
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Nanotechnology: Provides stable and soluble linkers for nanoparticle engineering.
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Drug Delivery: Serves as a thiol-reactive PEGylated linker in therapeutic design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use freshly prepared solutions; avoid repeated freeze–thaw cycles.
This product combines lipoamide surface anchoring with thiol-selective maleimide chemistry in a PEG11 backbone, specifically offering a versatile tool for conjugation, nanotechnology, and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
