PC SPDP-NHS Carbonate Ester (CAS: 2279944-61-3) is a photo-cleavable compound widely used in biochemical and pharmaceutical research for light-controlled biomolecule release.
Key Features
- Photo-Cleavable Linker: Breaks down under UV light to release attached molecules precisely.
- SPDP Group: Succinimidyl 3-(2-pyridyldithio)propionate forms stable disulfide bonds with thiol-containing molecules.
- NHS Group: Binds to primary amines, allowing stable biomolecule conjugation.
- Carbonate Ester: Forms strong covalent bonds with amines for stable molecular structures.
Applications
- Drug Delivery: Enables targeted and stable drug release, enhancing therapeutic precision.
- Bioconjugation: Facilitates cross-linking and attaching molecules, with the option for light-controlled release.
- Protein Labeling: Offers temporary labeling for proteins, removable by light exposure.
Advantages
- Precision: Provides exact control over molecular release using UV light.
- Versatility: Combines carbonate ester and NHS functionalities for stable biomolecule assembly.
Considerations
- Light Exposure: Requires precise light control for effective cleavage.
- Phototoxicity: Excessive light may affect nearby molecules or tissues.
PC SPDP-NHS Carbonate Ester is an essential tool in creating controlled drug delivery systems and conducting advanced biochemical research.
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