N,N-Bis(PEG2-azide)-N-amido-PEG2-oxyamine
This product is a multifunctional PEG linker featuring dual azide groups for click chemistry and an oxyamine group for oxime ligation. The PEG2 spacers impart solubility and compact flexibility, making it especially versatile for bioconjugation, probe development, and drug delivery applications.
Key Features and Benefits:
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Dual Azides: Support CuAAC or SPAAC click chemistry with alkynes.
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Oxyamine Group: Enables oxime ligation with aldehydes/ketones.
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PEG2 Spacers: Provide solubility and compact steric spacing.
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Orthogonal Reactivity: Allows stepwise multifunctional conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications:
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Bioconjugation: Couples biomolecules via azide and carbonyl chemistry.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Creates PEGylated scaffolds with dual reactivity.
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Synthetic Chemistry: Useful intermediate for advanced linker systems.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid prolonged exposure to moisture.
This product integrates dual click-reactive azides with oxime ligation chemistry in compact PEG2 spacers, specifically offering solubility and multifunctionality for advanced conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
