Mal-amido-PEG2-acid
This product is a heterobifunctional PEG linker containing a maleimide group, a PEG2 spacer, and a terminal carboxylic acid. It specifically enables thiol-specific conjugation and amide coupling, offering compact length, solubility, and dual functionality.
Key Features and Benefits
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Maleimide Group: Couples selectively with thiols to form stable thioether bonds.
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Carboxylic Acid: Reacts with amines to create stable amide linkages.
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PEG2 Spacer: Provides compact length and enhances solubility.
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Dual Reactivity: Combines thiol reactivity with carboxyl conjugation.
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High Purity: Ensures reproducibility in bioconjugation and synthesis workflows.
Applications
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Bioconjugation: Links thiol-containing biomolecules with amine-reactive partners.
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Probe Development: Builds multifunctional probes with orthogonal handles.
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Drug Delivery: Provides PEG scaffolds with thiol and amine coupling chemistry.
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Material Science: Functionalizes polymers, nanoparticles, and surfaces with dual reactive groups.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates maleimide thiol chemistry with carboxyl reactivity in a PEG2 scaffold, specifically offering compact, soluble, and versatile conjugation capability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
