| Catalog #: | AP10893 |
| Name: | TCO-PEG1-Val-Cit-PAB-OH |
| Chemical Formula: | C32H50N6O8 |
| Molecular Weight: | 646.79 |
| Purity: | ≥95% |
| Availability: | In Stock |
| SDS: | Download |
$750.00 – $1,980.00
TCO-PEG1-Val-Cit-PABC-OH is a useful tool for site specific bioconjugation. The TCO functional group undergoes bio-orthogonal reaction with tetrazine bearing biomolecule. The Val-Cit-PAB moiety is a very popular peptide sequence that can be site specifically cleaved by Cathepsin B enzyme.
| Unit | Price | Quantity | |
|---|---|---|---|
| 25 mg | $750 | ||
| 50 mg | $1180 | ||
| 100 mg | $1980 | ||
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TCO-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
