Mal-amido-PEG24 NHS Ester (CAS 2226733-37-3)
This is a versatile polyethylene glycol (PEG) linker with two functional groups:
- Maleimide group for reacting with thiol (-SH) groups.
- NHS ester for reacting with primary amines (-NH₂).
It’s designed for precision conjugation of molecules in biological and chemical applications.
Key Features
- Maleimide Group
- Forms stable bonds with thiol groups, enabling targeted conjugation with cysteine residues or other thiol-containing molecules.
- NHS Ester
- Reacts with primary amines to form stable amide bonds, useful for labeling proteins, peptides, or similar molecules.
- PEG Spacer (24 Units)
- Improves water solubility.
- Reduces steric hindrance and unwanted interactions.
- Enhances stability and bioavailability of conjugated molecules.
Mal-amido-PEG24 NHS Ester Applications
- Bioconjugation
- Attaches peptides, proteins, or biomolecules to surfaces or carriers for therapeutic and diagnostic uses.
- Antibody-Drug Conjugates (ADCs)
- Acts as a linker connecting drugs to antibodies for targeted cancer treatment.
- Protein Labeling
- Adds fluorescent markers, biotin, or other tags for detection and imaging.
- Surface Modification
- Modifies nanoparticles or polymers to improve biocompatibility and enable functionalization.
Product Information
- Chemical Formula: C₆₂H₁₁₁N₃O₃₁
- Molecular Weight: 1394.6 g/mol
- Purity: ≥95%
- Storage Conditions: Store at -20°C to ensure stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
