Azido-PEG9-acid
This product is a heterobifunctional PEG9 linker with a terminal azide for click chemistry and a carboxylic acid for amide coupling. The PEG9 spacer provides hydrophilicity, flexibility, and medium-to-long chain spacing, making it especially ideal for bioconjugation, drug delivery, and advanced material science.
Key Features and Benefits:
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Azide Group: Enables CuAAC and SPAAC click chemistry with alkynes.
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Carboxylic Acid Group: Couples efficiently with amines for stable amide bonds.
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PEG9 Spacer: Provides solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in demanding conjugation workflows.
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Dual Reactivity: Combines click-ready functionality with classical amide coupling.
Applications:
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Click Chemistry: Bioorthogonal azide–alkyne ligation for labeling and conjugation.
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Bioconjugation: Facilitates attachment of proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker enhances solubility, circulation time, and stability.
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Surface Functionalization: Functionalizes nanoparticles, polymers, hydrogels, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve azide and acid reactivity.
This product combines click-ready azide chemistry with carboxyl reactivity in a medium-length PEG chain, making it an especially versatile tool for multifunctional conjugation and drug delivery workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
