Mal-PEG-SCM

MAL-PEG-SCM is a linear heterobifunctional PEG reagent containing maleimide and succinimidyl NHS ester groups. Often used as a cross-linking agent or as a spacer between two different chemical entities. Maleimide reacts with thiol, SH, sulfhydryl or sulfhydryl, SCM stands for succinimide carboxymethyl ester and can react with primary amines. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. Applications are particularly suitable for the development of antibody drug conjugates (ADCs).