Folate-PEG-OH (Folic acid-PEG-OH) is a heterobifunctional PEG hydroxyl product of folate, which selectively binds tightly to folate receptors found in various cancer cells. Whereas the OH group can be further modified for bioconjugation. The PEG moiety in heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. The polymer can be used to develop drug carriers for cancer treatment.
Folate-PEG-OH is an organic compound used as a drug delivery system. It is a polyethylene glycol (PEG) linked to folic acid, which is used to target drugs and other molecules to folate receptor-expressing cells. This method of delivery has been used to improve the solubility and pharmacokinetic properties of drugs, as well as to increase their bioavailability.
