DBCO-PEG-Thiol

DBCO-PEG-Thiol is a compound that is widely used in pharmaceutical research and development due to its unique functional groups and properties. DBCO-PEG-Thiol is a bifunctional compound that contains a Dibenzocyclooctyne (DBCO) group, a Polyethylene glycol (PEG) chain, and a Thiol group. The DBCO group is a strained alkyne, which has a high reactivity with other functional groups, particularly azide groups. The PEG chain, on the other hand, provides a hydrophilic and biocompatible environment to the compound, while the thiol group provides the compound with the ability to bind to metallic surfaces.

In pharmaceutical research and development, DBCO-PEG-Thiol is commonly used as a linker molecule in drug conjugation. The compound can be used to connect a therapeutic agent to a targeting moiety, such as an antibody, to enhance the specificity of drug delivery.