Boc-Amine Alkyne-PEG-acid

Boc-Amine Alkyne-PEG-acid (Boc-amine alkyne-PEG-COOH, Alkyne Boc-amine-PEG-COOH) is a Boc-protected amine and alkyne group sharing one end and – the other end is a COOH group A trifunctional PEG derivative, which reacts with azide molecules via click chemistry in the presence of a copper catalyst to form triazole bonds. Carboxylic acids can react with amines in the presence of HATU or EDC to form amide bonds. tBoc-amines can be deprotected by acids (TFAs) to free amines that react with carboxylic acids and their active esters and isocyanates. It can also react with carbonyl groups such as ketones and aldehydes.