Boc-NH-PEG-Mal

Boc-NH-PEG-Maleimide is a compound commonly used in pharmaceutical research and development. It is a polyethylene glycol (PEG) derivative with a maleimide functional group at one end and a Boc-protected amine group at the other. The maleimide group is a highly reactive thiol-reactive moiety that can selectively react with cysteine residues in proteins to form stable thioether bonds. The Boc-protected amine group can be deprotected under mild acidic conditions to expose a primary amine for further functionalization.

The functional groups in Boc-NH-PEG-Maleimide make it a versatile compound in pharmaceutical research and development. Its thiol-reactive maleimide group makes it ideal for site-specific protein labeling, protein conjugation, and drug delivery systems. The PEG group provides solubility and stability to the compound, enhancing its biocompatibility and reducing non-specific interactions. Additionally, the Boc-protected amine group allows for further functionalization with various molecules, including fluorescent dyes, biotin, or other targeting ligands.