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Methyltetrazine-mPEG is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains a methyltetrazine functional group (-N4CH3) attached to a PEG chain. The methyltetrazine group is known for its ability to react selectively and rapidly with trans-cyclooctene (TCO) or cyclopropenone (CPO) groups, making Methyltetrazine-mPEG a powerful tool in the field of pharmaceutical research and development.

Methyltetrazine-mPEG has been extensively utilized in the development of bioorthogonal chemistry-based drug delivery systems, where it is used to conjugate therapeutic agents to TCO- or CPO-functionalized targeting molecules. The resulting conjugates exhibit excellent stability, high specificity, and low toxicity, making them promising candidates for targeted drug delivery and imaging applications.

In addition to drug delivery, Methyltetrazine-mPEG has also been employed in the development of imaging agents for various diagnostic applications. By conjugating Methyltetrazine-mPEG to fluorophores or radioisotopes, highly specific and sensitive imaging agents can be obtained, enabling the visualization of disease-related biomarkers in vivo.


Cat# Name Structure M.W. Purity Pricing
AP12579Methyltetrazine-mPEG, 5 kDa5000≥95% Pricing
AP12580Methyltetrazine-mPEG, 10 kDa10000≥95% Pricing

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