Acrylate PEG Succinimidyl Carboxymethyl Ester

Acrylate PEG Succinimidyl Carboxymethyl Ester (AC-PEG-SCM) is a linear heterobifunctional PEG reagent with acrylate and activated NHS ester. Often used as a cross-linking agent or as a spacer between two different chemical entities. Acrylates can be polymerized under the action of UV light or free radical initiators, and SCM is a type of NHS ester commonly known as succinimidylcarboxymethyl (SCM) ester. SCM is highly reactive with primary amines and forms stable amide bonds. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility and flexibility. Applications are particularly suitable for the development of antibody drug conjugates (ADCs).