Propargyl–PEG–CH2CO2–NHS ester is a functionalized polyethylene glycol (PEG) derivative used as a linker molecule in bioconjugation. This ester contains an NHS (N–hydroxysuccinimide) group that is reactive with primary amines, as well as a propargyl group that can be used for click chemistry reactions. It can be used to attach proteins, peptides, or other molecules to surfaces, nanoparticles, and other molecules.
This compound is a derivative of propargyl alcohol, which is a three-carbon molecule with a single triple bond, and is joined to a polyethylene glycol (PEG) chain. The NHS group is an amine group, and the ester group is a functional group that can react with other molecules.