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Propargyl-aliphatic-t-Boc(Alkyne-aliphatic-t-Boc) is belongs to the class of propargyl-containing aliphatic compounds. This compound contains a tert-butoxycarbonyl (t-Boc) protecting group attached to the terminal amine group (-NH2) and a propargyl functional group attached to the aliphatic chain. The propargyl functional group is known for its ability to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.

Propargyl-aliphatic-t-Boc has been extensively utilized in the synthesis of small molecules and bioconjugates, including drug molecules, imaging agents, and protein conjugates. The CuAAC reaction allows for the efficient and selective attachment of various functional groups, such as fluorescent dyes, biotin, or PEG, to the propargyl group, enabling the design and synthesis of novel compounds with tailored properties.

The t-Boc protecting group can be selectively removed under mild conditions, allowing for the selective deprotection of the terminal amine group and subsequent modification with other functional groups.


Cat# Name Structure M.W. Purity Pricing
AP14318tert-Butyl oct-7-yn-1-ylcarbamate225.30≥95% Pricing

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