PEG-Boc-PEG is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains a tert-butyloxycarbonyl (Boc) functional group attached to each end of a PEG chain.
PEG-Boc-PEG has been extensively utilized in the development of novel drug delivery systems, such as polymeric conjugates and hydrogels. Its unique chemical properties allow for the covalent attachment of therapeutic agents, such as peptides and proteins, to the PEG chain via amide bonds. The resulting conjugates exhibit improved stability, increased solubility, and prolonged circulation time in vivo, leading to enhanced therapeutic efficacy and reduced side effects.
In addition to its use in drug delivery systems, PEG-Boc-PEG has also been employed as a surface modifier in various biomedical applications.