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THP-PEG-Tos contains a tosylate functional group (-OTs) attached to a tetrahydropyran (THP) ring, which is in turn connected to a PEG chain.

THP-PEG-Tos has been widely utilized in the development of novel drug delivery systems, particularly in the preparation of prodrugs. A prodrug is an inactive or less active compound that is converted into an active drug through a metabolic process within the body. THP-PEG-Tos is often used as a prodrug linker, allowing for the covalent attachment of therapeutic agents to the PEG chain via a tosylate bond. The resulting conjugates are designed to be stable during circulation but can be activated by hydrolysis of the tosylate bond in the target tissue, leading to the release of the active drug.

THP-PEG-Tos has also been employed in the development of targeted drug delivery systems. By attaching targeting molecules such as antibodies or peptides to the PEG chain, the conjugates can selectively bind to specific cells or tissues, improving drug efficacy while reducing off-target effects.


Cat# Name Structure M.W. Purity Pricing
AP11180THP-SS-PEG1-Tos392.54≥95% Pricing
AP13879THP-PEG5-Tos432.5≥95% Pricing
AP11258THP-PEG8-Tos520.63≥95% Pricing

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