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PEG-bis(phosphonic acid diethyl ester) is a synthetic compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains two phosphonic acid groups and two ethyl ester groups, attached to the ends of a PEG chain.

The phosphonic acid groups in PEG-bis(phosphonic acid diethyl ester) enable it to bind strongly to metal ions, making it a useful chelator in various biomedical applications. It has been utilized in the development of bone-targeted drugs, such as bisphosphonates, which bind strongly to hydroxyapatite in bones, inhibiting bone resorption and promoting bone mineralization.

It has also been employed in the development of contrast agents for imaging techniques such as magnetic resonance imaging (MRI). The chelation of gadolinium ions to it allows for improved imaging contrast in MRI, enabling the visualization of specific tissues or structures in the body.

PEG-bis(phosphonic acid diethyl ester)

Cat# Name Structure M.W. Purity Pricing
AP11817PEG3-bis(phosphonic acid diethyl ester)378.29≥95% Pricing
AP11818PEG4-bis(phosphonic acid diethyl ester)422.35≥95% Pricing
AP11819PEG5-bis(phosphonic acid diethyl ester)466.4≥95% Pricing

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