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Ald-CH2-PEG-NHBoc is a chemical compound that has gained significant interest in the field of pharmaceutical research and development. It belongs to the family of PEGylated compounds and is a derivative of PEG (polyethylene glycol), which is a water-soluble polymer. The compound consists of an aldehyde group (Ald), a polyethylene glycol (PEG) chain, and a Boc-protected amine group (NHBoc).

The PEGylation process involves the covalent attachment of PEG to a biologically active molecule, such as a protein, peptide, or drug, to improve its pharmacokinetic and pharmacodynamic properties. PEGylation can increase the half-life of a drug, reduce its immunogenicity, and improve its solubility and stability, among other benefits.

Ald-CH2-PEG-NHBoc is often used as a linker molecule in the synthesis of PEGylated drugs and is particularly useful in the preparation of antibody-drug conjugates (ADCs), which are a promising class of targeted cancer therapies. The aldehyde group of Ald-CH2-PEG-NHBoc can react with the primary amine group of the antibody, while the Boc-protected amine group can react with the drug molecule, allowing for the controlled conjugation of the drug to the antibody.


Cat# Name Structure M.W. Purity Pricing
AP10071Ald-CH2-PEG2-NHBoc247.29≥95% Pricing
AP10070Ald-CH2-PEG3-NHBoc291.34≥95% Pricing
AP10072Ald-CH2-PEG4-NHBoc335.39≥95% Pricing

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