Methyltetrazine-PEG-STP Ester is a chemical compound that belongs to the class of PEG derivatives. This compound contains a tetrazine functional group and a STP ester group.
The tetrazine functional group (-N4) is known for its unique reactivity with trans-cyclooctene (TCO) through a bioorthogonal click reaction, allowing for site-specific labeling and bioconjugation. This feature makes Methyltetrazine-PEG-STP Ester a useful tool for imaging and tracking of drug delivery systems, as well as for targeted drug delivery.
The STP ester group (-OOCCH2CH2OCH2CH2NHS) is a cleavable linker that allows for controlled release of therapeutic agents from drug delivery systems. This feature is particularly valuable in the development of prodrug strategies, where the therapeutic agent is conjugated to the PEG chain via the STP ester group, and is subsequently released upon cleavage of the linker by esterases.
Methyltetrazine-PEG-STP Ester has been extensively utilized in the development of novel drug delivery systems, such as polymeric nanoparticles and liposomes. Its unique chemical properties allow for the site-specific conjugation of therapeutic agents, as well as for the controlled release of these agents from the drug delivery system.
Methyltetrazine-PEG-STP Ester
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP12646 | Methyltetrazine-PEG4-STP Ester | Pricing |
