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Methylamino-PEG-azide is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains an azide functional group (-N3) attached to one end of a PEG chain, and a methylamino group (-CH3NH-) attached to the other end.

The azide group is known for its ability to react with a variety of functional groups via click chemistry, enabling the rapid and efficient synthesis of complex molecules, including drug conjugates and bioconjugates. The methylamino group, on the other hand, can be used as a pH-responsive trigger for drug release, allowing for the selective delivery of therapeutic agents to specific tissues or cells.

Methylamino-PEG-azide has been extensively utilized in the development of novel drug delivery systems, such as polymer-drug conjugates, nanoparticles, and liposomes. Its unique chemical properties enable the covalent attachment of therapeutic agents, such as small molecules, peptides, and proteins, to the PEG chain via click chemistry. The resulting conjugates exhibit improved stability, enhanced pharmacokinetics, and reduced toxicity, leading to improved therapeutic efficacy.


Cat# Name Structure M.W. Purity Pricing
AP11606Methylamino-PEG3-azide232.28≥95% Pricing
AP11607Methylamino-PEG5-azide320.39≥95% Pricing

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