PTAD-PEG4-azide

PTAD-PEG4-Azide: Overview and Applications

Product Summary
PTAD-PEG4-Azide is a bioconjugation linker with a PTAD group for selective tyrosine labeling and an azide for click chemistry. The PEG4 spacer increases solubility and flexibility, making it well-suited for biological applications. This linker provides stable, targeted attachment to tyrosine residues in proteins, peptides, and small molecules, allowing for precise labeling and functionalization.

Key Benefits

• Tyrosine Selectivity: Targets only tyrosine, avoiding interference with other amino acids.
• Flexible PEG4 Spacer: Improves solubility and flexibility for easier labeling.
• Click Chemistry Ready: Azide group supports CuAAC click reactions for efficient conjugation.
• High Stability: Provides durable, stable linkage across different environments.

Applications of PTAD-PEG4-Azide

1. Bioconjugation and Labeling
   • Enables selective, stable tyrosine labeling for tracking proteins and peptides.
2. Click Chemistry
   • The azide group allows bioorthogonal CuAAC click chemistry with alkynes for versatile conjugation.
3. Drug Delivery
   • Supports targeted drug delivery with precise, stable attachment to biomolecules.
4. Surface Functionalization
   • Ideal for adding bioactive molecules to surfaces, enhancing biosensors and diagnostics.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.