DBCO-PEG2-DBCO (CAS: 2639395-48-3)
DBCO-PEG2-DBCO is a PEG linker with two azide-reactive DBCO groups at each end, ideal for copper-free click chemistry. It supports rapid and specific biomolecule conjugation, widely used in targeted drug delivery and imaging applications.
Key Features:
- Formula: C₄₄H₄₂N₄O₆
- Weight: 722.83 g/mol
- Functional Groups: Two DBCO moieties for azide reaction
- Solubility: Compatible with DMSO and DMF
- Copper-Free Click Chemistry: Fast, biocompatible, and specific binding to azides
Applications:
- Targeted Drug Delivery: Used in R&D to attach drugs to targeting molecules (e.g., antibodies) for highly specific, stable, and biocompatible drug conjugates.
- Bioconjugation: Supports the creation of antibody-drug conjugates and targeted therapeutics.
- Imaging Agents: Forms specific imaging probes by attaching fluorescent dyes or radionuclides for non-invasive disease detection.
- Polymer Crosslinking & Surface Modification: Links polymers and functionalizes surfaces for biosensors and diagnostics.
Storage & Handling:
- Store at -20°C, protected from light.
- Use PPE and ensure good ventilation during handling.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
